Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Mitigating myopia in tuberculosis.

Dunstan, Sarah J; Hawn, Thomas R.

Nat Immunol ; 22(6): 675-676, 2021 06.

Artigo em Inglês | MEDLINE | ID: mdl-34031615

2.

Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections.

Tobin, David M; Roca, Francisco J; Oh, Sungwhan F; McFarland, Ross; Vickery, Thad W; Ray, John P; Ko, Dennis C; Zou, Yuxia; Bang, Nguyen D; Chau, Tran T H; Vary, Jay C; Hawn, Thomas R; Dunstan, Sarah J; Farrar, Jeremy J; Thwaites, Guy E; King, Mary-Claire; Serhan, Charles N; Ramakrishnan, Lalita.

Cell ; 148(3): 434-46, 2012 Feb 03.

Artigo em Inglês | MEDLINE | ID: mdl-22304914

3.

Tuberculosis severity associates with variants and eQTLs related to vascular biology and infection-induced inflammation.

McHenry, Michael L; Simmons, Jason; Hong, Hyejeong; Malone, LaShaunda L; Mayanja-Kizza, Harriet; Bush, William S; Boom, W Henry; Hawn, Thomas R; Williams, Scott M; Stein, Catherine M.

PLoS Genet ; 19(3): e1010387, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36972313

4.

The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans.

Tobin, David M; Vary, Jay C; Ray, John P; Walsh, Gregory S; Dunstan, Sarah J; Bang, Nguyen D; Hagge, Deanna A; Khadge, Saraswoti; King, Mary-Claire; Hawn, Thomas R; Moens, Cecilia B; Ramakrishnan, Lalita.

Cell ; 140(5): 717-30, 2010 Mar 05.

Artigo em Inglês | MEDLINE | ID: mdl-20211140

5.

Kimma: flexible linear mixed effects modeling with kinship covariance for RNA-seq data.

Dill-McFarland, Kimberly A; Mitchell, Kiana; Batchu, Sashank; Segnitz, Richard Max; Benson, Basilin; Janczyk, Tomasz; Cox, Madison S; Mayanja-Kizza, Harriet; Boom, William Henry; Benchek, Penelope; Stein, Catherine M; Hawn, Thomas R; Altman, Matthew C.

Bioinformatics ; 39(5)2023 05 04.

Artigo em Inglês | MEDLINE | ID: mdl-37140544

6.

TOLLIP Optimizes Dendritic Cell Maturation to Lipopolysaccharide and Mycobacterium tuberculosis.

Venkatasubramanian, Sambasivan; Pryor, Robyn; Plumlee, Courtney; Cohen, Sarah B; Simmons, Jason D; Warr, Alexander J; Graustein, Andrew D; Saha, Aparajita; Hawn, Thomas R; Urdahl, Kevin B; Shah, Javeed A.

J Immunol ; 209(3): 435-445, 2022 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-35803695

7.

REL and BHLHE40 Variants Are Associated with IL-12 and IL-10 Responses and Tuberculosis Risk.

Shah, Javeed A; Warr, Alex J; Graustein, Andrew D; Saha, Aparajita; Dunstan, Sarah J; Thuong, Nguyen T T; Thwaites, Guy E; Caws, Maxine; Thai, Phan V K; Bang, Nguyen D; Chau, Tran T H; Khor, Chiea Chuen; Li, Zheng; Hibberd, Martin; Chang, Xuling; Nguyen, Felicia K; Hernandez, Carlo A; Jones, Madison A; Sassetti, Christopher M; Fitzgerald, Katherine A; Musvosvi, Munyaradzi; Gela, Anele; Hanekom, Willem A; Hatherill, Mark; Scriba, Thomas J; Hawn, Thomas R.

J Immunol ; 208(6): 1352-1361, 2022 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-35217585

8.

Sensitive Blood-Based Detection of HIV-1 and Mycobacterium tuberculosis Peptides for Disease Diagnosis by Immuno-Affinity Liquid Chromatography-Tandem Mass Spectrometry: A Method Development and Proof-of-Concept Study.

Li, Lin; Lyon, Christopher J; LaCourse, Sylvia M; Zheng, Wenshu; Stern, Joshua; Escudero, Jaclyn N; Murithi, Wilfred Bundi; Njagi, Lilian; John-Stewart, Grace; Hawn, Thomas R; Nduba, Videlis; Abdelgaliel, Wael; Tombler, Thomas; Horne, David; Jiang, Li; Hu, Tony Y.

Clin Chem ; 69(12): 1409-1419, 2023 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-37956323

9.

Cumulative Mycobacterium tuberculosis Infection Incidence (Measured Primarily by Tuberculin Skin Test) Among Infants With Human Immunodeficiency Virus Exposure: Observational Follow-up of an Isoniazid Prophylaxis Trial.

LaCourse, Sylvia M; Escudero, Jaclyn N; Mecha, Jerphason; Warr, A J; Richardson, Barbra A; Carimo, Naziat; Cranmer, Lisa M; Maleche-Obimbo, Elizabeth; Matemo, Daniel; Kinuthia, John; Hawn, Thomas R; John-Stewart, Grace.

Clin Infect Dis ; 75(12): 2253-2256, 2022 12 19.

Artigo em Inglês | MEDLINE | ID: mdl-35607710

10.

Inflammasome Genetic Variants, Macrophage Function, and Clinical Outcomes in Cystic Fibrosis.

Graustein, Andrew D; Berrington, William R; Buckingham, Kati J; Nguyen, Felicia K; Joudeh, Lara L; Rosenfeld, Margaret; Bamshad, Michael J; Gibson, Ronald L; Hawn, Thomas R; Emond, Mary J.

Am J Respir Cell Mol Biol ; 65(2): 157-166, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-33848452

11.

Genetic Variation in Toll-Like Receptor 5 and Colonization with Flagellated Bacterial Vaginosis-Associated Bacteria.

Dela Cruz, Erin J; Fiedler, Tina L; Liu, Congzhou; Munch, Matthew M; Kohler, Christina M; Oot, Antoinette R; Wallis, Jacqueline M; Wang, Junhui; Frishman, Anna; Garcia, Kristina; Wiser, Andrew; Balkus, Jennifer E; Srinivasan, Sujatha; Golob, Jonathan L; Sycuro, Laura K; Marrazzo, Jeanne M; Hawn, Thomas R; Fredricks, David N.

Infect Immun ; 89(3)2021 02 16.

Artigo em Inglês | MEDLINE | ID: mdl-33199356

12.

A Randomized Controlled Trial of Isoniazid to Prevent Mycobacterium tuberculosis Infection in Kenyan Human Immunodeficiency Virus-Exposed Uninfected Infants.

LaCourse, Sylvia M; Richardson, Barbra A; Kinuthia, John; Warr, A J; Maleche-Obimbo, Elizabeth; Matemo, Daniel; Cranmer, Lisa M; Mecha, Jerphason; Escudero, Jaclyn N; Hawn, Thomas R; John-Stewart, Grace.

Clin Infect Dis ; 73(2): e337-e344, 2021 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-32564076

13.

Latent Tuberculosis Infection and Subclinical Coronary Atherosclerosis in Peru and Uganda.

Huaman, Moises A; De Cecco, Carlo N; Bittencourt, Marcio S; Ticona, Eduardo; Kityo, Cissy; Ballena, Isabel; Nalukwago, Sophie; Nazzinda, Rashidah; Ticona, Cesar; Azañero, Ruben; Zhang, Bin; Farquhar, Carey; Hawn, Thomas R; Sterling, Timothy R; Fichtenbaum, Carl J; Longenecker, Chris T.

Clin Infect Dis ; 73(9): e3384-e3390, 2021 11 02.

Artigo em Inglês | MEDLINE | ID: mdl-33388766

14.

Nicotinamide Limits Replication of Mycobacterium tuberculosis and Bacille Calmette-Guérin Within Macrophages.

Simmons, Jason D; Peterson, Glenna J; Campo, Monica; Lohmiller, Jenny; Skerrett, Shawn J; Tunaru, Sorin; Offermanns, Stefan; Sherman, David R; Hawn, Thomas R.

J Infect Dis ; 221(6): 989-999, 2020 03 02.

Artigo em Inglês | MEDLINE | ID: mdl-31665359

15.

The common HAQ STING variant impairs cGAS-dependent antibacterial responses and is associated with susceptibility to Legionnaires' disease in humans.

Ruiz-Moreno, Juan S; Hamann, Lutz; Shah, Javeed A; Verbon, Annelies; Mockenhaupt, Frank P; Puzianowska-Kuznicka, Monika; Naujoks, Jan; Sander, Leif E; Witzenrath, Martin; Cambier, John C; Suttorp, Norbert; Schumann, Ralf R; Jin, Lei; Hawn, Thomas R; Opitz, Bastian.

PLoS Pathog ; 14(1): e1006829, 2018 01.

Artigo em Inglês | MEDLINE | ID: mdl-29298342

16.

Nontuberculous Mycobacteria and Heterologous Immunity to Tuberculosis.

Shah, Javeed A; Lindestam Arlehamn, Cecilia S; Horne, David J; Sette, Alessandro; Hawn, Thomas R.

J Infect Dis ; 220(7): 1091-1098, 2019 08 30.

Artigo em Inglês | MEDLINE | ID: mdl-31165861

17.

Remembering the Host in Tuberculosis Drug Development.

Frank, Daniel J; Horne, David J; Dutta, Noton K; Shaku, Moagi Tube; Madensein, Rajhmun; Hawn, Thomas R; Steyn, Adrie J C; Karakousis, Petros C; Kana, Bavesh Davandra; Meintjes, Graeme; Laughon, Barbara; Tanvir, Zaid.

J Infect Dis ; 219(10): 1518-1524, 2019 04 19.

Artigo em Inglês | MEDLINE | ID: mdl-30590592

18.

Fine-mapping analysis of a chromosome 2 region linked to resistance to Mycobacterium tuberculosis infection in Uganda reveals potential regulatory variants.

Igo, Robert P; Hall, Noémi B; Malone, LaShaunda L; Hall, Jacob B; Truitt, Barbara; Qiu, Feiyou; Tao, Li; Mupere, Ezekiel; Schnell, Audrey; Hawn, Thomas R; Bush, William S; Joloba, Moses; Boom, W Henry; Stein, Catherine M.

Genes Immun ; 20(6): 473-483, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-30100616

19.

Long-term Stability of Resistance to Latent Mycobacterium tuberculosis Infection in Highly Exposed Tuberculosis Household Contacts in Kampala, Uganda.

Stein, Catherine M; Nsereko, Mary; Malone, LaShaunda L; Okware, Brenda; Kisingo, Hussein; Nalukwago, Sophie; Chervenak, Keith; Mayanja-Kizza, Harriet; Hawn, Thomas R; Boom, W Henry.

Clin Infect Dis ; 68(10): 1705-1712, 2019 05 02.

Artigo em Inglês | MEDLINE | ID: mdl-30165605

20.

New tricks for old dogs: countering antibiotic resistance in tuberculosis with host-directed therapeutics.

Hawn, Thomas R; Shah, Javeed A; Kalman, Daniel.

Immunol Rev ; 264(1): 344-62, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25703571

BVS Doenças Infecciosas e Parasitárias

Informação e Conhecimento para a Saúde

Configurar filtros

Sua seleção (0)

Formato de exportação:

Exportar: